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Saturday 14 January 2012

Freely "Explore" the Pediatric Cancer Genome Project data

St. Jude Children’s Research Hospital announced in a press release the launch of “Explore”, a freely available website for published research results from the St. Jude Children’s Research Hospital – Washington University Pediatric Cancer Genome Project (PCGP). The PCGP is the largest effort to date aimed at sequencing the entire genomes of both normal and cancer cells from pediatric cancer patients, comparing differences in the DNA to identify genetic mistakes that lead to childhood cancers (see my previous post).
The Explore website is designed to expand access to high-quality genomic data related to pediatric cancers, accelerate discovery and hypothesis testing, and provide comprehensive visualizations of the data. Explore is also designed to make it easier for clinical and basic researchers to search published results from the PCGP. Explore allows researchers to access the genome project’s unique, published data specific to pediatric cancers and to make discoveries of their own.
I tried to play with Explore, after a simple registration obtained by providing my email address. The site is quite sophisticated but not always intuitive and at times apparently unresponsive. One should know that right now the access is granted to 16.3% of the 600 cancer genome data (only the published ones), corresponding T-ALL and RB tumors. Data include Copy Number Variation, Single Nucleotide Variations, Structural Variations and Gene Expression.

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