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Wednesday, 6 June 2012

Hepatocellular carcinoma on GigaDB: another avalanche of free data for the scientific community

The Asian Cancer Research Group has released on GigaDB the raw data from its project on Hepatocellular Carcinoma. This is a really huge dataset including 30X whole genome sequences from both health and tumor tissues obtained from 88 asian patients. And if it may be not enough to satisfy your data-analysis desires, raw data from gene expression analysis on these samples are also available deposited in the GEO database.
From the project's web site: "Genomic DNA was purified for at least 30-fold coverage paired-end (PE) sequencing, and PE reads were mapped on human reference genome (UCSC build hg19) and HBV (NC_003977). Two sequencing libraries with different insert size were constructed for each genomic DNA sample (200bp and 800bp). Paired end, 90bp read length sequencing was performed in the HiSeq 2000 sequencer according to the manufacturer’s instructions. Raw gene expression profiling data of these human HCC samples have been deposited to GEO with the accession number GSE25097."
The study has been recently described in a letter to Nature Genetics (Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma).

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